Bile Acid Analog Intercepts Liver Fibrosis

نویسندگان

  • C. Daniel De Magalhaes Filho
  • Michael Downes
  • Ron Evans
چکیده

Ocaliva, a synthetic bile acid analog with high affinity for the nuclear bile acid receptor FXR, is effective in treating primary biliary cholangitis, an autoimmune liver disease. It works in patients who fail to respond to or cannot tolerate conventional treatment with the natural bile acid ursodeoxycholic acid (UDCA).

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عنوان ژورنال:
  • Cell

دوره 166  شماره 

صفحات  -

تاریخ انتشار 2016