Bile Acid Analog Intercepts Liver Fibrosis
نویسندگان
چکیده
Ocaliva, a synthetic bile acid analog with high affinity for the nuclear bile acid receptor FXR, is effective in treating primary biliary cholangitis, an autoimmune liver disease. It works in patients who fail to respond to or cannot tolerate conventional treatment with the natural bile acid ursodeoxycholic acid (UDCA).
منابع مشابه
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عنوان ژورنال:
- Cell
دوره 166 شماره
صفحات -
تاریخ انتشار 2016